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MutTMPredictor: Robust and accurate cascade XGBoost classifier for prediction of mutations in transmembrane proteins
Transmembrane proteins have critical biological functions and play a role in a multitude of cellular processes including cell signaling, transport of molecules and ions across membranes. Approximately 60% of transmembrane proteins are considered as drug targets. Missense mutations in such proteins c...
Autores principales: | Ge, Fang, Zhu, Yi-Heng, Xu, Jian, Muhammad, Arif, Song, Jiangning, Yu, Dong-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649221/ https://www.ncbi.nlm.nih.gov/pubmed/34938415 http://dx.doi.org/10.1016/j.csbj.2021.11.024 |
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