Cargando…

Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database

BACKGROUND: The usefulness of right heart catherization (RHC) has long been debated, and thus, we aimed to study the real‐world impact of the use of RHC in cardiogenic shock. METHODS AND RESULTS: In the Nationwide Readmissions Database using International Classification of Diseases, Tenth Revision (...

Descripción completa

Detalles Bibliográficos
Autores principales: Ranka, Sagar, Mastoris, Ioannis, Kapur, Navin K., Tedford, Ryan J., Rali, Aniket, Acharya, Prakash, Weidling, Robert, Goyal, Amandeep, Sauer, Andrew J., Gupta, Bhanu, Haglund, Nicholas, Gupta, Kamal, Fang, James C., Lindenfeld, JoAnn, Shah, Zubair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649238/
https://www.ncbi.nlm.nih.gov/pubmed/34423652
http://dx.doi.org/10.1161/JAHA.120.019843
_version_ 1784610951131037696
author Ranka, Sagar
Mastoris, Ioannis
Kapur, Navin K.
Tedford, Ryan J.
Rali, Aniket
Acharya, Prakash
Weidling, Robert
Goyal, Amandeep
Sauer, Andrew J.
Gupta, Bhanu
Haglund, Nicholas
Gupta, Kamal
Fang, James C.
Lindenfeld, JoAnn
Shah, Zubair
author_facet Ranka, Sagar
Mastoris, Ioannis
Kapur, Navin K.
Tedford, Ryan J.
Rali, Aniket
Acharya, Prakash
Weidling, Robert
Goyal, Amandeep
Sauer, Andrew J.
Gupta, Bhanu
Haglund, Nicholas
Gupta, Kamal
Fang, James C.
Lindenfeld, JoAnn
Shah, Zubair
author_sort Ranka, Sagar
collection PubMed
description BACKGROUND: The usefulness of right heart catherization (RHC) has long been debated, and thus, we aimed to study the real‐world impact of the use of RHC in cardiogenic shock. METHODS AND RESULTS: In the Nationwide Readmissions Database using International Classification of Diseases, Tenth Revision (ICD‐1 0), we identified 236 156 patient hospitalizations with cardiogenic shock between 2016 and 2017. We sought to evaluate the impact of RHC during index hospitalization on management strategies, complications, and outcomes as well as on 30‐day readmission rate. A total 25 840 patients (9.6%) received RHC on index admission. The RHC group had significantly more comorbidities compared with the non‐RHC group. During the index admission, the RHC group had lower death (25.8% versus 39.5%, P<0.001) and stroke rates (3.1% versus 3.4%, P<0.001). Thirty‐day readmission rates (18.7% versus 19.7%, P=0.04) and death on readmission (7.9% versus 9.3%, P=0.03) were also lower in the RHC group. After adjustment, RHC was associated with lower index admission mortality (odds ratio, 0.69; 95% CI, 0.66–0.72), lower stroke rate (odds ratio, 0.81; 95% CI, 0.72–0.90), lower 30‐day readmission (odds ratio, 0.83; 95% CI, 0.78–0.88), and higher left ventricular assist device implantations/orthotopic heart transplants (odds ratio, 6.05; 95% CI, 4.43–8.28) during rehospitalization. Results were not meaningfully different after excluding patients with cardiac arrest. CONCLUSIONS: RHC use in cardiogenic shock is associated with improved outcomes and increased use of downstream advanced heart failure therapies. Further blinded randomized studies are required to confirm our findings.
format Online
Article
Text
id pubmed-8649238
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-86492382022-01-14 Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database Ranka, Sagar Mastoris, Ioannis Kapur, Navin K. Tedford, Ryan J. Rali, Aniket Acharya, Prakash Weidling, Robert Goyal, Amandeep Sauer, Andrew J. Gupta, Bhanu Haglund, Nicholas Gupta, Kamal Fang, James C. Lindenfeld, JoAnn Shah, Zubair J Am Heart Assoc Original Research BACKGROUND: The usefulness of right heart catherization (RHC) has long been debated, and thus, we aimed to study the real‐world impact of the use of RHC in cardiogenic shock. METHODS AND RESULTS: In the Nationwide Readmissions Database using International Classification of Diseases, Tenth Revision (ICD‐1 0), we identified 236 156 patient hospitalizations with cardiogenic shock between 2016 and 2017. We sought to evaluate the impact of RHC during index hospitalization on management strategies, complications, and outcomes as well as on 30‐day readmission rate. A total 25 840 patients (9.6%) received RHC on index admission. The RHC group had significantly more comorbidities compared with the non‐RHC group. During the index admission, the RHC group had lower death (25.8% versus 39.5%, P<0.001) and stroke rates (3.1% versus 3.4%, P<0.001). Thirty‐day readmission rates (18.7% versus 19.7%, P=0.04) and death on readmission (7.9% versus 9.3%, P=0.03) were also lower in the RHC group. After adjustment, RHC was associated with lower index admission mortality (odds ratio, 0.69; 95% CI, 0.66–0.72), lower stroke rate (odds ratio, 0.81; 95% CI, 0.72–0.90), lower 30‐day readmission (odds ratio, 0.83; 95% CI, 0.78–0.88), and higher left ventricular assist device implantations/orthotopic heart transplants (odds ratio, 6.05; 95% CI, 4.43–8.28) during rehospitalization. Results were not meaningfully different after excluding patients with cardiac arrest. CONCLUSIONS: RHC use in cardiogenic shock is associated with improved outcomes and increased use of downstream advanced heart failure therapies. Further blinded randomized studies are required to confirm our findings. John Wiley and Sons Inc. 2021-08-21 /pmc/articles/PMC8649238/ /pubmed/34423652 http://dx.doi.org/10.1161/JAHA.120.019843 Text en © 2021 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Research
Ranka, Sagar
Mastoris, Ioannis
Kapur, Navin K.
Tedford, Ryan J.
Rali, Aniket
Acharya, Prakash
Weidling, Robert
Goyal, Amandeep
Sauer, Andrew J.
Gupta, Bhanu
Haglund, Nicholas
Gupta, Kamal
Fang, James C.
Lindenfeld, JoAnn
Shah, Zubair
Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title_full Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title_fullStr Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title_full_unstemmed Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title_short Right Heart Catheterization in Cardiogenic Shock Is Associated With Improved Outcomes: Insights From the Nationwide Readmissions Database
title_sort right heart catheterization in cardiogenic shock is associated with improved outcomes: insights from the nationwide readmissions database
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649238/
https://www.ncbi.nlm.nih.gov/pubmed/34423652
http://dx.doi.org/10.1161/JAHA.120.019843
work_keys_str_mv AT rankasagar rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT mastorisioannis rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT kapurnavink rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT tedfordryanj rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT ralianiket rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT acharyaprakash rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT weidlingrobert rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT goyalamandeep rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT sauerandrewj rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT guptabhanu rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT haglundnicholas rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT guptakamal rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT fangjamesc rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT lindenfeldjoann rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase
AT shahzubair rightheartcatheterizationincardiogenicshockisassociatedwithimprovedoutcomesinsightsfromthenationwidereadmissionsdatabase