Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression

BACKGROUND: While numerous interventions effectively interfered with abdominal aortic aneurysm (AAA) formation/progression in preclinical models, none of the successes translated into clinical success. Hence, a systematic exploration of parallel and divergent processes in clinical AAA disease and it...

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Detalles Bibliográficos
Autores principales: Gäbel, Gabor, Northoff, Bernd H., Balboa, Amanda, Becirovic‐ Agic, Mediha, Petri, Marcelo, Busch, Albert, Maegdefessel, Lars, Mahlmann, Adrian, Ludwig, Stefan, Teupser, Daniel, de Waard, Vivian, Golledge, Jonathan, Wanhainen, Anders, Wågsäter, Dick, Holdt, Lesca M., Lindeman, Jan H. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649280/
https://www.ncbi.nlm.nih.gov/pubmed/34420357
http://dx.doi.org/10.1161/JAHA.120.020231

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