Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy

In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the matter. However, the authors appear to misquote findings, fail...

Descripción completa

Detalles Bibliográficos
Autores principales: Klitgaard, Thomas Lass, Schjørring, Olav Lilleholt, Nielsen, Frederik Mølgaard, Meyhoff, Christian Sylvest, Barbateskovic, Marija, Wetterslev, Jørn, Perner, Anders, Rasmussen, Bodil Steen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649324/
https://www.ncbi.nlm.nih.gov/pubmed/34876227
http://dx.doi.org/10.1186/s40560-021-00573-5
_version_ 1784610972353167360
author Klitgaard, Thomas Lass
Schjørring, Olav Lilleholt
Nielsen, Frederik Mølgaard
Meyhoff, Christian Sylvest
Barbateskovic, Marija
Wetterslev, Jørn
Perner, Anders
Rasmussen, Bodil Steen
author_facet Klitgaard, Thomas Lass
Schjørring, Olav Lilleholt
Nielsen, Frederik Mølgaard
Meyhoff, Christian Sylvest
Barbateskovic, Marija
Wetterslev, Jørn
Perner, Anders
Rasmussen, Bodil Steen
author_sort Klitgaard, Thomas Lass
collection PubMed
description In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the matter. However, the authors appear to misquote findings, fail to report results for all specified analyses, do not identify all relevant trials, have post hoc changed the eligibility criteria, and have seemingly switched directions of effects in analyses of secondary outcomes. These issues have led to incorrect conclusions concerning the effects of targeted oxygen therapy in critically ill patients.
format Online
Article
Text
id pubmed-8649324
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-86493242021-12-07 Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy Klitgaard, Thomas Lass Schjørring, Olav Lilleholt Nielsen, Frederik Mølgaard Meyhoff, Christian Sylvest Barbateskovic, Marija Wetterslev, Jørn Perner, Anders Rasmussen, Bodil Steen J Intensive Care Letter to the Editor In a recent paper, Chen et al. report the findings of a systematic review with meta-analysis concerning conservative versus conventional oxygen therapy for critically ill patients. We wish to commend the authors for their interest in the matter. However, the authors appear to misquote findings, fail to report results for all specified analyses, do not identify all relevant trials, have post hoc changed the eligibility criteria, and have seemingly switched directions of effects in analyses of secondary outcomes. These issues have led to incorrect conclusions concerning the effects of targeted oxygen therapy in critically ill patients. BioMed Central 2021-12-07 /pmc/articles/PMC8649324/ /pubmed/34876227 http://dx.doi.org/10.1186/s40560-021-00573-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Letter to the Editor
Klitgaard, Thomas Lass
Schjørring, Olav Lilleholt
Nielsen, Frederik Mølgaard
Meyhoff, Christian Sylvest
Barbateskovic, Marija
Wetterslev, Jørn
Perner, Anders
Rasmussen, Bodil Steen
Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title_full Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title_fullStr Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title_full_unstemmed Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title_short Letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
title_sort letter the editor: serious methodological concerns about a recently published meta-analysis on oxygen therapy
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649324/
https://www.ncbi.nlm.nih.gov/pubmed/34876227
http://dx.doi.org/10.1186/s40560-021-00573-5
work_keys_str_mv AT klitgaardthomaslass lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT schjørringolavlilleholt lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT nielsenfrederikmølgaard lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT meyhoffchristiansylvest lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT barbateskovicmarija lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT wetterslevjørn lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT perneranders lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy
AT rasmussenbodilsteen lettertheeditorseriousmethodologicalconcernsaboutarecentlypublishedmetaanalysisonoxygentherapy

Ejemplares similares