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UCP3 (Uncoupling Protein 3) Insufficiency Exacerbates Left Ventricular Diastolic Dysfunction During Angiotensin II‐Induced Hypertension

BACKGROUND: Left ventricular diastolic dysfunction, an early stage in the pathogenesis of heart failure with preserved ejection fraction, is exacerbated by joint exposure to hypertension and obesity; however, the molecular mechanisms involved remain uncertain. The mitochondrial UCP3 (uncoupling prot...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Ashraf, Sadia, Ashraf, Nadia, Harmancey, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649532/
https://www.ncbi.nlm.nih.gov/pubmed/34533037
http://dx.doi.org/10.1161/JAHA.121.022556