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Non-clinical assessment of safety, biodistribution and tumorigenicity of human mesenchymal stromal cells

Guidelines regulating the development of advanced therapy medicinal products (ATMPs) request nonclinical data for toxicity, biodistribution and tumorigenicity before mesenchymal stromal cell (MSC) products can be administered in large clinical trials. We assessed the biodistribution/persistence, saf...

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Detalles Bibliográficos
Autores principales:	Thäte, Claudia, Woischwill, Christiane, Brandenburg, Gunda, Müller, Matthias, Böhm, Sonja, Baumgart, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649581/ https://www.ncbi.nlm.nih.gov/pubmed/34926173 http://dx.doi.org/10.1016/j.toxrep.2021.11.016

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