High-LET Carbon and Iron Ions Elicit a Prolonged and Amplified p53 Signaling and Inflammatory Response Compared to low-LET X-Rays in Human Peripheral Blood Mononuclear Cells

Understanding the differences in biological response to photon and particle radiation is important for optimal exploitation of particle therapy for cancer patients, as well as for the adequate application of radiation protection measures for astronauts. To address this need, we compared the transcri...

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Detalles Bibliográficos
Autores principales: Macaeva, Ellina, Tabury, Kevin, Michaux, Arlette, Janssen, Ann, Averbeck, Nicole, Moreels, Marjan, De Vos, Winnok H., Baatout, Sarah, Quintens, Roel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649625/
https://www.ncbi.nlm.nih.gov/pubmed/34888245
http://dx.doi.org/10.3389/fonc.2021.768493

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