Transcriptomic Characterization of Tuberculous Sputum Reveals a Host Warburg Effect and Microbial Cholesterol Catabolism

The crucial transmission phase of tuberculosis (TB) relies on infectious sputum and yet cannot easily be modeled. We applied one-step RNA sequencing (RNA-Seq) to sputum from infectious TB patients to investigate the host and microbial environments underlying transmission of Mycobacterium tuberculosi...

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Detalles Bibliográficos
Autores principales: Lai, Rachel P. J., Cortes, Teresa, Marais, Suzaan, Rockwood, Neesha, Burke, Melissa L., Garza-Garcia, Acely, Horswell, Stuart, Sesay, Abdul K., O’Garra, Anne, Young, Douglas B., Wilkinson, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649757/
https://www.ncbi.nlm.nih.gov/pubmed/34872348
http://dx.doi.org/10.1128/mBio.01766-21

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