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OXA-23 β-Lactamase Overexpression in Acinetobacter baumannii Drives Physiological Changes Resulting in New Genetic Vulnerabilities

β-Lactamase expression is the major mechanism of resistance to penicillins, cephalosporins, and carbapenems in the multidrug-resistant (MDR) bacterium Acinetobacter baumannii. In fact, stable high-level expression of at least one β-lactamase has been rapidly increasing and reported to occur in up to...

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Detalles Bibliográficos
Autores principales:	Colquhoun, Jennifer M., Farokhyfar, Marjan, Hutcheson, Anna R., Anderson, Alexander, Bethel, Christopher R., Bonomo, Robert A., Clarke, Anthony J., Rather, Philip N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649759/ https://www.ncbi.nlm.nih.gov/pubmed/34872351 http://dx.doi.org/10.1128/mBio.03137-21

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