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hPMSCs-Derived Exosomal miRNA-21 Protects Against Aging-Related Oxidative Damage of CD4(+) T Cells by Targeting the PTEN/PI3K-Nrf2 Axis

Mesenchymal stem cells (MSCs)-derived exosomes were considered a novel therapeutic approach in many aging-related diseases. This study aimed to clarify the protective effects of human placenta MSCs-derived exosomes (hPMSC-Exo) in aging-related CD4(+) T cell senescence and identified the underlying m...

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Detalles Bibliográficos
Autores principales:	Xiong, Yanlian, Xiong, Yanlei, Zhang, Hengchao, Zhao, Yaxuan, Han, Kaiyue, Zhang, Jiashen, Zhao, Dongmei, Yu, Zhenhai, Geng, Ziran, Wang, Longfei, Wang, Yueming, Luan, Xiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8649962/ https://www.ncbi.nlm.nih.gov/pubmed/34887868 http://dx.doi.org/10.3389/fimmu.2021.780897

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