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Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

[Image: see text] Reaction of thiazoline fused 2-pyridones with alkyl halides in the presence of cesium carbonate opens the thiazoline ring via S-alkylation and generates N-alkenyl functionalized 2-pyridones. In the reaction with propargyl bromide, the thiazoline ring opens and subsequently closes v...

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Detalles Bibliográficos
Autores principales:	Tyagi, Mohit, Adolfsson, Dan E., Singh, Pardeep, Ådén, Jörgen, Jayaweera, Sanduni Wasana, Gharibyan, Anna, Bharate, Jaideep B., Kiss, Anita, Sarkar, Souvik, Olofsson, Anders, Almqvist, Fredrik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650012/ https://www.ncbi.nlm.nih.gov/pubmed/34767366 http://dx.doi.org/10.1021/acs.joc.1c01875

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