Soluble TREM‐1, as a new ligand for the membrane receptor Robo2, promotes hepatic stellate cells activation and liver fibrosis

Triggering receptor expressed on myeloid cells‐1 (TREM‐1) exists in two forms: a transmembrane form and a soluble form (sTREM‐1). The levels of sTREM‐1 are elevated in supernatants of activated HSCs. However, the role of sTREM‐1 in HSC activation and liver fibrosis remains undefined. Previous studie...

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Detalles Bibliográficos
Autores principales: Liu, Ting, Chen, Shujia, Xie, Xiaoli, Liu, Hongqun, Wang, Yongjuan, Qi, Shengbin, Shi, Linping, Zhou, Xue, Zhang, Jiuna, Wang, Shuling, Wang, Yijun, Chen, Shengxiong, Dou, Shiying, Jiang, Xiaoyu, Cui, Ruolin, Jiang, Huiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650037/
https://www.ncbi.nlm.nih.gov/pubmed/34750987
http://dx.doi.org/10.1111/jcmm.17033

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