The Sigma‐2 Receptor/TMEM97 Agonist PB28 Suppresses Cell Proliferation and Invasion by Regulating the PI3K‐AKT‐mTOR Signalling Pathway in Renal Cancer

Sigma‐2 receptor/TMEM97 is overexpressed in many tumours, and sigma‐2 receptor ligands are under investigation for cancer therapy. We intended to evaluate the effect of PB28 on renal cancer in proliferation, migration and invasion in vitro and in vivo. Invasive renal cancer cell lines treated with P...

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Detalles Bibliográficos
Autores principales: Zhan, Bo, Zhang, Zhe, Piao, Chiyuan, Dong, Xiao, Du, Yang, Kong, Chuize, Jiang, Yuanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650047/
https://www.ncbi.nlm.nih.gov/pubmed/34783163
http://dx.doi.org/10.1111/jcmm.17047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650047/
https://www.ncbi.nlm.nih.gov/pubmed/34783163
http://dx.doi.org/10.1111/jcmm.17047

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