Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization

[Image: see text] We report an efficient method for the preparation of synthetically valuable trisubstituted alkenylboronate esters through alkene isomerization of their readily available 1,1-disubstituted regioisomeric counterparts. Either stereoisomer of the target alkenylboronate motif can be obt...

Descripción completa

Detalles Bibliográficos
Autores principales: Segura, Lucas, Massad, Itai, Ogasawara, Masamichi, Marek, Ilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650100/
https://www.ncbi.nlm.nih.gov/pubmed/34766777
http://dx.doi.org/10.1021/acs.orglett.1c03513
_version_ 1784611137855160320
author Segura, Lucas
Massad, Itai
Ogasawara, Masamichi
Marek, Ilan
author_facet Segura, Lucas
Massad, Itai
Ogasawara, Masamichi
Marek, Ilan
author_sort Segura, Lucas
collection PubMed
description [Image: see text] We report an efficient method for the preparation of synthetically valuable trisubstituted alkenylboronate esters through alkene isomerization of their readily available 1,1-disubstituted regioisomeric counterparts. Either stereoisomer of the target alkenylboronate motif can be obtained at will from the same starting material by employing different isomerization catalysts.
format Online
Article
Text
id pubmed-8650100
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher American Chemical Society
record_format MEDLINE/PubMed
spelling pubmed-86501002021-12-08 Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization Segura, Lucas Massad, Itai Ogasawara, Masamichi Marek, Ilan Org Lett [Image: see text] We report an efficient method for the preparation of synthetically valuable trisubstituted alkenylboronate esters through alkene isomerization of their readily available 1,1-disubstituted regioisomeric counterparts. Either stereoisomer of the target alkenylboronate motif can be obtained at will from the same starting material by employing different isomerization catalysts. American Chemical Society 2021-11-12 2021-12-03 /pmc/articles/PMC8650100/ /pubmed/34766777 http://dx.doi.org/10.1021/acs.orglett.1c03513 Text en © 2021 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Segura, Lucas
Massad, Itai
Ogasawara, Masamichi
Marek, Ilan
Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title_full Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title_fullStr Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title_full_unstemmed Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title_short Stereodivergent Access to Trisubstituted Alkenylboronate Esters through Alkene Isomerization
title_sort stereodivergent access to trisubstituted alkenylboronate esters through alkene isomerization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650100/
https://www.ncbi.nlm.nih.gov/pubmed/34766777
http://dx.doi.org/10.1021/acs.orglett.1c03513
work_keys_str_mv AT seguralucas stereodivergentaccesstotrisubstitutedalkenylboronateestersthroughalkeneisomerization
AT massaditai stereodivergentaccesstotrisubstitutedalkenylboronateestersthroughalkeneisomerization
AT ogasawaramasamichi stereodivergentaccesstotrisubstitutedalkenylboronateestersthroughalkeneisomerization
AT marekilan stereodivergentaccesstotrisubstitutedalkenylboronateestersthroughalkeneisomerization

Ejemplares similares