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Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development

Sonic hedgehog (Shh) signaling regulates multiple morphogenetic processes during embryonic neurogenesis and craniofacial skeletal development. Gpr161 is a known negative regulator of Shh signaling. Nullizygous Gpr161 mice are embryonic lethal, presenting with structural defects involving the neural...

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Detalles Bibliográficos
Autores principales:	Kim, Sung-Eun, Robles-Lopez, Karla, Cao, Xuanye, Liu, Kristyn, Chothani, Pooja J., Bhavani, Nikitha, Rahman, Lauren, Mukhopadhyay, Saikat, Wlodarczyk, Bogdan J., Finnell, Richard H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650154/ https://www.ncbi.nlm.nih.gov/pubmed/34887903 http://dx.doi.org/10.3389/fgene.2021.761418

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