Dual Targeting by Inhibition of Phosphoinositide-3-Kinase and Mammalian Target of Rapamycin Attenuates the Neuroinflammatory Responses in Murine Hippocampal Cells and Seizures in C57BL/6 Mice

Emerging evidence suggests the association of seizures and inflammation; however, underlying cell signaling mechanisms are still not fully understood. Overactivation of phosphoinositide-3-kinases is associated with both neuroinflammation and seizures. Herein, we speculate the PI3K/Akt/mTOR pathway a...

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Detalles Bibliográficos
Autores principales: Vyas, Preeti, Tulsawani, Rajkumar, Vohora, Divya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650161/
https://www.ncbi.nlm.nih.gov/pubmed/34887852
http://dx.doi.org/10.3389/fimmu.2021.739452

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650161/
https://www.ncbi.nlm.nih.gov/pubmed/34887852
http://dx.doi.org/10.3389/fimmu.2021.739452

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