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Optimization of metabolism to improve efficacy during CAR-T cell manufacturing

Chimeric antigen receptor T cell (CAR-T cell) therapy is a relatively new, effective, and rapidly evolving therapeutic for adoptive immunotherapies. Although it has achieved remarkable effect in hematological malignancies, there are some problems that remain to be resolved. For example, there are hi...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Jin, Xin, Sun, Rui, Xiong, Xia, Wang, Jiaxi, Xie, Danni, Zhao, MingFeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650271/
https://www.ncbi.nlm.nih.gov/pubmed/34876185
http://dx.doi.org/10.1186/s12967-021-03165-x