Femtomolar and locus-specific detection of N(6)-methyladenine in DNA by integrating double-hindered replication and nucleic acid-functionalized MB@Zr-MOF

In this study, a novel electrochemical biosensor was constructed for ultrasensitive and locus-specific detection of N(6)-Methyladenine (m(6)A) in DNA using double-hindered replication and nucleic acid-coated methylene blue (MB)@Zr-MOF. Based on the combination of m(6)A-impeded replication and Ag(I)-...

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Detalles Bibliográficos
Autores principales: Zheng, Qingyuan, Wang, Tong, Li, Xinmin, Qian, Husun, Bian, Xintong, Li, Xingrong, Bai, Huijie, Ding, Shijia, Yan, Yurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650346/
https://www.ncbi.nlm.nih.gov/pubmed/34876148
http://dx.doi.org/10.1186/s12951-021-01156-0

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