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pVHL-mediated SMAD3 degradation suppresses TGF-β signaling

Transforming growth factor β (TGF-β) signaling plays a fundamental role in metazoan development and tissue homeostasis. However, the molecular mechanisms concerning the ubiquitin-related dynamic regulation of TGF-β signaling are not thoroughly understood. Using a combination of proteomics and an siR...

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Detalles Bibliográficos
Autores principales:	Zhou, Jun, Dabiri, Yasamin, Gama-Brambila, Rodrigo A., Ghafoory, Shahrouz, Altinbay, Mukaddes, Mehrabi, Arianeb, Golriz, Mohammad, Blagojevic, Biljana, Reuter, Stefanie, Han, Kang, Seidel, Anna, Đikić, Ivan, Wölfl, Stefan, Cheng, Xinlai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650352/ https://www.ncbi.nlm.nih.gov/pubmed/34860252 http://dx.doi.org/10.1083/jcb.202012097

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