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Co-administration of human MSC overexpressing HIF-1α increases human CD34(+) cell engraftment in vivo

BACKGROUND: Poor graft function or graft failure after allogeneic stem cell transplantation is an unmet medical need, in which mesenchymal stromal cells (MSC) constitute an attractive potential therapeutic approach. Hypoxia-inducible factor-1α (HIF-1α) overexpression in MSC (HIF-MSC) potentiates the...

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Detalles Bibliográficos
Autores principales:	Preciado, Silvia, Sirerol-Piquer, Mª Salomé, Muntión, Sandra, Osugui, Lika, Martí-Chillón, Gerardo J., Navarro-Bailón, Almudena, Sepúlveda, Pilar, Sánchez-Guijo, Fermín
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650423/ https://www.ncbi.nlm.nih.gov/pubmed/34876206 http://dx.doi.org/10.1186/s13287-021-02669-z

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