Cargando…
Catalase deficiency facilitates the shuttling of free fatty acid to brown adipose tissue through lipolysis mediated by ROS during sustained fasting
BACKGROUND: Fatty acids (FA) derived from adipose tissue and liver serve as the main fuel in thermogenesis of brown adipose tissue (BAT). Catalase, a peroxisomal enzyme, plays an important role in maintaining intracellular redox homeostasis by decomposing hydrogen peroxide to either water or oxygen...
Autores principales: | Dutta, Raghbendra Kumar, Lee, Joon No, Maharjan, Yunash, Park, Channy, Choe, Seong-Kyu, Ho, Ye-Shih, Park, Raekil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650429/ https://www.ncbi.nlm.nih.gov/pubmed/34876210 http://dx.doi.org/10.1186/s13578-021-00710-5 |
Ejemplares similares
-
Catalase-deficient mice induce aging faster through lysosomal dysfunction
por: Dutta, Raghbendra Kumar, et al.
Publicado: (2022) -
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell
por: Mu, Yizhu, et al.
Publicado: (2021) -
TMEM135 regulates primary ciliogenesis through modulation of intracellular cholesterol distribution
por: Maharjan, Yunash, et al.
Publicado: (2020) -
Intracellular cholesterol transport inhibition Impairs autophagy flux by decreasing autophagosome–lysosome fusion
por: Maharjan, Yunash, et al.
Publicado: (2022) -
Knockdown of PEX16 Induces Autophagic Degradation of Peroxisomes
por: Wei, Xiaofan, et al.
Publicado: (2021)