Cargando…
Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation
BACKGROUND: Critically ill patients often experience several transitions of care following critical illness. Research has explored the challenges which patients have with medication management across these transitions. It is unclear whether patients admitted to critical care due to COVID-19 will hav...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650475/ https://www.ncbi.nlm.nih.gov/pubmed/34872966 http://dx.doi.org/10.1136/bmjresp-2021-001037 |
_version_ | 1784611204326490112 |
---|---|
author | MacTavish, Pamela McPeake, Joanne Breslin, Antoin Forrest, Ruth Kishore, Rakesh MacGregor, Fiona Oprey, Alison Quasim, Tara Shaw, Martin |
author_facet | MacTavish, Pamela McPeake, Joanne Breslin, Antoin Forrest, Ruth Kishore, Rakesh MacGregor, Fiona Oprey, Alison Quasim, Tara Shaw, Martin |
author_sort | MacTavish, Pamela |
collection | PubMed |
description | BACKGROUND: Critically ill patients often experience several transitions of care following critical illness. Research has explored the challenges which patients have with medication management across these transitions. It is unclear whether patients admitted to critical care due to COVID-19 will have similar challenges. The aim of this study was to explore medication management in critical care survivors following severe COVID-19. METHODS: Between 3 and 7 months post hospital discharge, patients who had been admitted to critical care due to severe COVID-19 were invited to an established recovery service. During the clinic consultation a medication review was performed by a pharmacist. This included medicines reconciliation, assessing the appropriateness of each of the prescribed medications and identification of medication changes. We also assessed changes to pain management in the discharge period. RESULTS: In total, 78 patients had a full medication review available. Over 70% of patients were taking an increased dose of medicine or a new medicine at clinic. There was a significant overall increase in new medication during the clinic consultation, across different British National Formulary classifications (OR: 1.73 (95% CI: 1.28 to 2.34), p<0.001). Compared with pre critical care admission, there was a significant increase in the number of patients taking regular analgesia following severe COVID-19 infection (23 (29.5%) vs 39 (50%), p<0.001). CONCLUSION: Following severe COVID-19, patients may require new or increasing doses of medicines. Ongoing review of these patients is crucial to ensure optimal outcomes. |
format | Online Article Text |
id | pubmed-8650475 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-86504752021-12-22 Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation MacTavish, Pamela McPeake, Joanne Breslin, Antoin Forrest, Ruth Kishore, Rakesh MacGregor, Fiona Oprey, Alison Quasim, Tara Shaw, Martin BMJ Open Respir Res Critical Care BACKGROUND: Critically ill patients often experience several transitions of care following critical illness. Research has explored the challenges which patients have with medication management across these transitions. It is unclear whether patients admitted to critical care due to COVID-19 will have similar challenges. The aim of this study was to explore medication management in critical care survivors following severe COVID-19. METHODS: Between 3 and 7 months post hospital discharge, patients who had been admitted to critical care due to severe COVID-19 were invited to an established recovery service. During the clinic consultation a medication review was performed by a pharmacist. This included medicines reconciliation, assessing the appropriateness of each of the prescribed medications and identification of medication changes. We also assessed changes to pain management in the discharge period. RESULTS: In total, 78 patients had a full medication review available. Over 70% of patients were taking an increased dose of medicine or a new medicine at clinic. There was a significant overall increase in new medication during the clinic consultation, across different British National Formulary classifications (OR: 1.73 (95% CI: 1.28 to 2.34), p<0.001). Compared with pre critical care admission, there was a significant increase in the number of patients taking regular analgesia following severe COVID-19 infection (23 (29.5%) vs 39 (50%), p<0.001). CONCLUSION: Following severe COVID-19, patients may require new or increasing doses of medicines. Ongoing review of these patients is crucial to ensure optimal outcomes. BMJ Publishing Group 2021-12-06 /pmc/articles/PMC8650475/ /pubmed/34872966 http://dx.doi.org/10.1136/bmjresp-2021-001037 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Critical Care MacTavish, Pamela McPeake, Joanne Breslin, Antoin Forrest, Ruth Kishore, Rakesh MacGregor, Fiona Oprey, Alison Quasim, Tara Shaw, Martin Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title | Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title_full | Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title_fullStr | Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title_full_unstemmed | Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title_short | Evaluation of medication changes following severe COVID-19 infection: a multicentre evaluation |
title_sort | evaluation of medication changes following severe covid-19 infection: a multicentre evaluation |
topic | Critical Care |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650475/ https://www.ncbi.nlm.nih.gov/pubmed/34872966 http://dx.doi.org/10.1136/bmjresp-2021-001037 |
work_keys_str_mv | AT mactavishpamela evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT mcpeakejoanne evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT breslinantoin evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT forrestruth evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT kishorerakesh evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT macgregorfiona evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT opreyalison evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT quasimtara evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation AT shawmartin evaluationofmedicationchangesfollowingseverecovid19infectionamulticentreevaluation |