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Switching Between LC-ESI-MS/MS and EMIT Methods for Routine TDM of Valproic Acid in Pediatric Patients With Epilepsy: What Clinicians and Researchers Need to Know

Background: Valproic acid (VPA) is a widely used antiseizure medication and its dosing needs to be tailored individually through therapeutic drug monitoring (TDM) to avoid or prevent toxicity. Currently, immune-enzymatic assays such as Enzyme Multiplied Immunoassay Technique (EMIT), and Liquid Chrom...

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Detalles Bibliográficos
Autores principales:	Xia, Ying, Long, Jia-Yi, Shen, Meng-Yuan, Dong, Na, Guo, Hong-Li, Hu, Ya-Hui, Lu, Xiao-Peng, Ding, Xuan-Sheng, Chen, Feng, Qiu, Jin-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650496/ https://www.ncbi.nlm.nih.gov/pubmed/34887756 http://dx.doi.org/10.3389/fphar.2021.750744

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