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Successful Milk Oral Immunotherapy Promotes Generation of Casein-Specific CD137(+) FOXP3(+) Regulatory T Cells Detectable in Peripheral Blood
BACKGROUND: Oral immunotherapy (OIT) is an emerging treatment for cow’s milk protein (CMP) allergy in children. The mechanisms driving tolerance following OIT are not well understood. Regulatory T cells (T(REG)) cells are key inhibitors of allergic responses and promoters of allergen-specific tolera...
Autores principales: | Zhang, Yi, Li, Lei, Genest, Geneviève, Zhao, Wei, Ke, Dan, Bartolucci, Sabrina, Pavey, Nils, Al-Aubodah, Tho-Alfakar, Lejtenyi, Duncan, Torabi, Bahar, Ben-Shoshan, Moshe, Mazer, Bruce, Piccirillo, Ciriaco A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650635/ https://www.ncbi.nlm.nih.gov/pubmed/34887847 http://dx.doi.org/10.3389/fimmu.2021.705615 |
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