An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2

The TIPE2 (tumor necrosis factor-alpha-induced protein 8-like 2) protein is a major regulator of cancer and inflammatory diseases. The availability of its sequence and structure, as well as the critical amino acids involved in its ligand binding, provides insights into its function and helps greatly...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Haiping, Li, Junxin, Saravanan, Konda Mani, Wu, Hao, Wang, Zhichao, Wu, Du, Wei, Yanjie, Lu, Zhen, Chen, Youhai H., Wan, Xiaochun, Pan, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650684/
https://www.ncbi.nlm.nih.gov/pubmed/34887765
http://dx.doi.org/10.3389/fphar.2021.772296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650684/
https://www.ncbi.nlm.nih.gov/pubmed/34887765
http://dx.doi.org/10.3389/fphar.2021.772296

Ejemplares similares