The Zebrafish Antiapoptotic Protein BIRC2 Promotes Edwardsiella piscicida Infection by Inhibiting Caspases and Accumulating p53 in a p53 Transcription-Dependent and -Independent Manner

IAPs (inhibitors of apoptosis) are endogenous caspase inhibitors with multiple biological activities. In the present study, we show functional characteristics of antiapoptotic protein BIRC2 (cIAP1) in response to Edwardsiella piscicida infection. Overexpression of BIRC2 in zebrafish larvae promoted...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Yan, Dong, Xiao, Jun, Feng, Hao, Chang, Ming Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650707/
https://www.ncbi.nlm.nih.gov/pubmed/34887869
http://dx.doi.org/10.3389/fimmu.2021.781680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650707/
https://www.ncbi.nlm.nih.gov/pubmed/34887869
http://dx.doi.org/10.3389/fimmu.2021.781680

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