A GWAS top hit for circulating leptin is associated with weight gain but not with leptin protein levels in lithium-augmented patients with major depression

Lithium-treated patients often suffer from weight gain as a common adverse event. In an earlier investigation, we found an impact of two single-nucleotide polymorphisms (rs10487506 and rs2278815) at the leptin gene on weight gain but not on leptin protein levels in serum under lithium augmentation....

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Detalles Bibliográficos
Autores principales: Bopp, Sandra K, Heilbronner, Urs, Schlattmann, Peter, Buspavanich, Pichit J, Lang, Undine E, Heinz, Andreas, Schulze, Thomas G, Adli, Mazda, Mühleisen, Thomas W, Ricken, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650825/
https://www.ncbi.nlm.nih.gov/pubmed/34653833
http://dx.doi.org/10.1016/j.euroneuro.2021.09.007

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