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Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation

INTRODUCTION: Paraspinal abscesses are most commonly caused by Staphylococcus aureus and some Gram-negative bacteria. In developing countries, Mycobacterium tuberculosis (MTB) contributes to almost 50 % of cases. Even in proven cases of tubercular paraspinal abscesses, secondary infection of aerobic...

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Autores principales: Sreenivasan, Priya, Sharma, Bhawna, Singh, Apinderpreet, Kataria, Mandeep Singh, Ray, Pallab, Angrup, Archana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650847/
https://www.ncbi.nlm.nih.gov/pubmed/34888482
http://dx.doi.org/10.1099/acmi.0.000253
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author Sreenivasan, Priya
Sharma, Bhawna
Singh, Apinderpreet
Kataria, Mandeep Singh
Ray, Pallab
Angrup, Archana
author_facet Sreenivasan, Priya
Sharma, Bhawna
Singh, Apinderpreet
Kataria, Mandeep Singh
Ray, Pallab
Angrup, Archana
author_sort Sreenivasan, Priya
collection PubMed
description INTRODUCTION: Paraspinal abscesses are most commonly caused by Staphylococcus aureus and some Gram-negative bacteria. In developing countries, Mycobacterium tuberculosis (MTB) contributes to almost 50 % of cases. Even in proven cases of tubercular paraspinal abscesses, secondary infection of aerobic or anaerobic bacteria is possible and should be carefully evaluated for proper management. CASE REPORT: A type I diabetes mellitus patient presented with chronic backache and lower limb weakness and radiological investigations showed paraspinal collections suggestive of tuberculosis. The patient was then started on anti-tubercular drugs, she initially responded and then showed gradual deterioration in the form of increased pain, fever and pus discharge. Aerobic cultures of pus were sterile and anaerobic culture grew Peptoniphilus asaccharolyticus sensitive to metronidazole. Appropriate treatment had resulted in clinical improvement. CONCLUSION: Suspicion about co-infection with aerobic or anaerobic bacteria should be high even in proven cases of tubercular paraspinal abscess not improving despite proper anti-tubercular therapy.
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spelling pubmed-86508472021-12-08 Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation Sreenivasan, Priya Sharma, Bhawna Singh, Apinderpreet Kataria, Mandeep Singh Ray, Pallab Angrup, Archana Access Microbiol Case Reports INTRODUCTION: Paraspinal abscesses are most commonly caused by Staphylococcus aureus and some Gram-negative bacteria. In developing countries, Mycobacterium tuberculosis (MTB) contributes to almost 50 % of cases. Even in proven cases of tubercular paraspinal abscesses, secondary infection of aerobic or anaerobic bacteria is possible and should be carefully evaluated for proper management. CASE REPORT: A type I diabetes mellitus patient presented with chronic backache and lower limb weakness and radiological investigations showed paraspinal collections suggestive of tuberculosis. The patient was then started on anti-tubercular drugs, she initially responded and then showed gradual deterioration in the form of increased pain, fever and pus discharge. Aerobic cultures of pus were sterile and anaerobic culture grew Peptoniphilus asaccharolyticus sensitive to metronidazole. Appropriate treatment had resulted in clinical improvement. CONCLUSION: Suspicion about co-infection with aerobic or anaerobic bacteria should be high even in proven cases of tubercular paraspinal abscess not improving despite proper anti-tubercular therapy. Microbiology Society 2021-08-03 /pmc/articles/PMC8650847/ /pubmed/34888482 http://dx.doi.org/10.1099/acmi.0.000253 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution NonCommercial License. The Microbiology Society waived the open access fees for this article.
spellingShingle Case Reports
Sreenivasan, Priya
Sharma, Bhawna
Singh, Apinderpreet
Kataria, Mandeep Singh
Ray, Pallab
Angrup, Archana
Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title_full Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title_fullStr Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title_full_unstemmed Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title_short Secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: A rare presentation
title_sort secondary anaerobic infection in a case of multidrug resistant tubercular paraspinal abscess: a rare presentation
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8650847/
https://www.ncbi.nlm.nih.gov/pubmed/34888482
http://dx.doi.org/10.1099/acmi.0.000253
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