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Therapeutic Potential of Exosomal circRNA Derived from Synovial Mesenchymal Cells via Targeting circEDIL3/miR-485-3p/PIAS3/STAT3/VEGF Functional Module in Rheumatoid Arthritis

BACKGROUND: Synovial inflammation and its associated activation of angiogenesis play critical roles in rheumatoid arthritis (RA). Exosomes, as carriers of genetic information including circular RNAs (circRNAs), have been explored as delivery vehicles for therapeutic molecules. However, the effects o...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, Zhang, Yue, Ma, Yeye, Luo, Lili, Chu, Maolin, Zhang, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651050/
https://www.ncbi.nlm.nih.gov/pubmed/34887661
http://dx.doi.org/10.2147/IJN.S333465