Cargando…

Gene excavation and expression analysis of CYP and UGT related to the post modifying stage of gypenoside biosynthesis in Gynostemma pentaphyllum (Thunb.) Makino by comprehensive analysis of RNA and proteome sequencing

Previous studies have revealed that gypenosides produced from Gynostemma pentaphyllum (Thunb.) Makino are mainly dammarane-type triterpenoid saponins with diverse structures and important biological activities, but the mechanism of diversity for gypenoside biosynthesis is still unclear. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yangmei, Chen, Qicong, Huang, Yuanheng, Zhao, Ruiqiang, Sun, Jian, Yuan, Xidong, Xu, Huiming, Liu, Huiyu, Wu, Yaosheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651138/ https://www.ncbi.nlm.nih.gov/pubmed/34874937 http://dx.doi.org/10.1371/journal.pone.0260027

Ejemplares similares

Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan)
por: Li, Yantao, et al.
Publicado: (2016)

Network pharmacology analysis reveals neuroprotection of Gynostemma pentaphyllum (Thunb.) Makino in Alzheimer’ disease
por: Wang, Jiahao, et al.
Publicado: (2022)

In Vitro Anticancer Activity of a Nonpolar Fraction from Gynostemma pentaphyllum (Thunb.) Makino
por: Li, Yantao, et al.
Publicado: (2016)

Isolation, Structures, and Bioactivities of the Polysaccharides from Gynostemma pentaphyllum (Thunb.) Makino: A Review
por: Ji, Xiaolong, et al.
Publicado: (2018)

Bioassay-guided isolation and identification of anticancer and antioxidant compounds from Gynostemma pentaphyllum (Thunb.) Makino
por: Wang, Tian-Xing, et al.
Publicado: (2018)

Uncovering the molecular mechanism of Gynostemma pentaphyllum (Thunb.) Makino against breast cancer using network pharmacology and molecular docking
por: Wang, Wen-Xiang, et al.
Publicado: (2022)

Hybrid sequencing of the Gynostemma pentaphyllum transcriptome provides new insights into gypenoside biosynthesis
por: Liang, Tongtong, et al.
Publicado: (2019)

Chromosome-level genome assembly of Gynostemma pentaphyllum provides insights into gypenoside biosynthesis
por: Huang, Ding, et al.
Publicado: (2021)

Immunomodulatory and Antioxidant Effects of Polysaccharides from Gynostemma pentaphyllum Makino in Immunosuppressed Mice
por: Shang, Xiaoya, et al.
Publicado: (2016)

Transcriptome Sequencing of Gynostemma pentaphyllum to Identify Genes and Enzymes Involved in Triterpenoid Biosynthesis
por: Chen, Qicong, et al.
Publicado: (2016)

Effects of Plant Elicitors on Growth and Gypenosides Biosynthesis in Cell Culture of Giao co lam (Gynostemma pentaphyllum)
por: Quang, Hoang Tan, et al.
Publicado: (2022)

Gynostemma pentaphyllum extract and its active component gypenoside L improve the exercise performance of treadmill-trained mice
por: Kim, Yoon Hee, et al.
Publicado: (2022)

Gypenoside A from Gynostemma pentaphyllum Attenuates Airway Inflammation and Th2 Cell Activities in a Murine Asthma Model
por: Huang, Wen-Chung, et al.
Publicado: (2022)

Chemical composition of tetraploid Gynostemma pentaphyllum gypenosides and their suppression on inflammatory response by NF‐κB/MAPKs/AP‐1 signaling pathways
por: Wang, Bo, et al.
Publicado: (2020)

Gypenoside XVII, an Active Ingredient from Gynostemma Pentaphyllum, Inhibits C3aR-Associated Synaptic Pruning in Stressed Mice
por: Zhang, Man-Man, et al.
Publicado: (2022)

Diploid chromosome-level reference genome and population genomic analyses provide insights into Gypenoside biosynthesis and demographic evolution of Gynostemma pentaphyllum (Cucurbitaceae)
por: Zhang, Xiao, et al.
Publicado: (2022)

The Effect of Gynostemma pentaphyllum Extract on Mouse Dermal Fibroblasts
por: Lobo, Sara Nadia, et al.
Publicado: (2014)

New Dammarane-Type Saponins from Gynostemma pentaphyllum
por: Chen, Po-Yen, et al.
Publicado: (2019)

Transcriptomics and metabolomics association analysis revealed the responses of Gynostemma pentaphyllum to cadmium
por: Zhou, Yunyi, et al.
Publicado: (2023)

Genome-Wide Identification of R2R3-MYB Transcription Factors: Discovery of a “Dual-Function” Regulator of Gypenoside and Flavonol Biosynthesis in Gynostemma pentaphyllum
por: Huang, Ding, et al.
Publicado: (2022)

Gynostemma pentaphyllum is neuroprotective in a rat model of cardiopulmonary resuscitation
por: Keilhoff, Gerburg, et al.
Publicado: (2017)

Complete chloroplast genome sequence of the medicinal plant Gynostemma pentaphyllum
por: Zeng, Xin-Yi, et al.
Publicado: (2016)

Gynostemma pentaphyllum extract and Gypenoside L enhance skeletal muscle differentiation and mitochondrial metabolism by activating the PGC-1α pathway in C2C12 myotubes
por: Kim, Yoon Hee, et al.
Publicado: (2022)

Metabonomics Study of the Therapeutic Mechanism of Gynostemma pentaphyllum and Atorvastatin for Hyperlipidemia in Rats
por: Wang, Miao, et al.
Publicado: (2013)

Restoration of Electric Footshock-Induced Immunosuppression in Mice by Gynostemma pentaphyllum Components
por: Im, Sun-A, et al.
Publicado: (2012)

Bifidobacterium animalis: the missing link for the cancer-preventive effect of Gynostemma pentaphyllum
por: Liao, Weilin, et al.
Publicado: (2020)

Progress in the Medicinal Value, Bioactive Compounds, and Pharmacological Activities of Gynostemma pentaphyllum
por: Su, Chao, et al.
Publicado: (2021)

Gynostemma pentaphyllum for dyslipidemia: A systematic review of randomized controlled trials
por: Dai, Ning, et al.
Publicado: (2022)

Amelioration of hepatic steatosis is associated with modulation of gut microbiota and suppression of hepatic miR-34a in Gynostemma pentaphylla (Thunb.) Makino treated mice
por: Jia, Ning, et al.
Publicado: (2018)

Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients
por: Huyen, V. T. T., et al.
Publicado: (2013)

Caco-2 Cell Permeability of Flavonoids and Saponins from Gynostemma pentaphyllum: the Immortal Herb
por: Ahmed, Iftekhar, et al.
Publicado: (2020)

Complete chloroplast genome sequence of Gynostemma pentaphyllum (Cucurbitaceae), a perennial medicinal herb
por: Shi, Yancai, et al.
Publicado: (2019)

Effect of Polysaccharide Extracted From Gynostemma Pentaphyllum on the Body Weight and Gut Microbiota of Mice
por: Li, Shiwei, et al.
Publicado: (2022)

Molecular Mechanisms of Gynostemma pentaphyllum in Prevention and Treatment of Non-Small-Cell Lung Cancer
por: Liang, Renji, et al.
Publicado: (2022)

The Content and Principle of the Rare Ginsenosides Produced from Gynostemma pentaphyllum after Heat Treatment
por: Li, Xin-Can, et al.
Publicado: (2023)

Gynostemma Pentaphyllum Increases Exercise Performance and Alters Mitochondrial Respiration and AMPK in Healthy Males
por: Nayyar, Deepti, et al.
Publicado: (2023)

Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients
por: Huyen, V. T. T., et al.
Publicado: (2012)

Evaluation of Antidiabetic Effects of the Traditional Medicinal Plant Gynostemma pentaphyllum and the Possible Mechanisms of Insulin Release
por: Lokman, Ezarul Faradianna, et al.
Publicado: (2015)

Population genetic structure, migration, and polyploidy origin of a medicinal species Gynostemma pentaphyllum (Cucurbitaceae)
por: Zhang, Xiao, et al.
Publicado: (2019)

Anxiolytic Effects of Herbal Ethanol Extract from Gynostemma pentaphyllum in Mice after Exposure to Chronic Stress
por: Choi, Hyun Sook, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_p3qnqdjvo9i7cq388i15tiv472