Modulation of pulsatile GnRH dynamics across the ovarian cycle via changes in the network excitability and basal activity of the arcuate kisspeptin network

Pulsatile GnRH release is essential for normal reproductive function. Kisspeptin secreting neurons found in the arcuate nucleus, known as KNDy neurons for co-expressing neurokinin B, and dynorphin, drive pulsatile GnRH release. Furthermore, gonadal steroids regulate GnRH pulsatile dynamics across th...

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Detalles Bibliográficos
Autores principales: Voliotis, Margaritis, Li, Xiao Feng, De Burgh, Ross Alexander, Lass, Geffen, Ivanova, Deyana, McIntyre, Caitlin, O'Byrne, Kevin, Tsaneva-Atanasova, Krasimira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651288/
https://www.ncbi.nlm.nih.gov/pubmed/34787076
http://dx.doi.org/10.7554/eLife.71252

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