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Cilengitide Inhibits Neovascularization in a Rabbit Abdominal Aortic Plaque Model by Impairing the VEGF Signaling

BACKGROUND: Cilengitide is a selective α(v)β(3) and α(v)β(5) integrin inhibitor. We sought to investigate the effect of cilengitide on the neovascularization of abdominal aortic plaques in rabbits and explore its underlying antiangiogenic mechanism on human umbilical vein endothelial cells (HUVECs)....

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Detalles Bibliográficos
Autores principales:	Zhu, Fawang, Yuan, Shuai, Li, Jing, Mou, Yun, Hu, Zhiqiang, Wang, Xiuqin, Sun, Xiaotong, Ding, Jie, Zheng, Zhelan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651393/ https://www.ncbi.nlm.nih.gov/pubmed/34888383 http://dx.doi.org/10.1155/2021/5954757

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