Hypoxia Regulates Endogenous Double-Stranded RNA Production via Reduced Mitochondrial DNA Transcription

Hypoxia is a common phenomenon in solid tumours strongly linked to the hallmarks of cancer. Hypoxia promotes local immunosuppression and downregulates type I interferon (IFN) expression and signalling, which contribute to the success of many cancer therapies. Double-stranded RNA (dsRNA), transiently...

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Detalles Bibliográficos
Autores principales: Arnaiz, Esther, Miar, Ana, Dias Junior, Antonio Gregorio, Prasad, Naveen, Schulze, Ulrike, Waithe, Dominic, Nathan, James A., Rehwinkel, Jan, Harris, Adrian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651540/
https://www.ncbi.nlm.nih.gov/pubmed/34900733
http://dx.doi.org/10.3389/fonc.2021.779739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651540/
https://www.ncbi.nlm.nih.gov/pubmed/34900733
http://dx.doi.org/10.3389/fonc.2021.779739

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