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Hypoxia Regulates Endogenous Double-Stranded RNA Production via Reduced Mitochondrial DNA Transcription

Hypoxia is a common phenomenon in solid tumours strongly linked to the hallmarks of cancer. Hypoxia promotes local immunosuppression and downregulates type I interferon (IFN) expression and signalling, which contribute to the success of many cancer therapies. Double-stranded RNA (dsRNA), transiently...

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Detalles Bibliográficos
Autores principales:	Arnaiz, Esther, Miar, Ana, Dias Junior, Antonio Gregorio, Prasad, Naveen, Schulze, Ulrike, Waithe, Dominic, Nathan, James A., Rehwinkel, Jan, Harris, Adrian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651540/ https://www.ncbi.nlm.nih.gov/pubmed/34900733 http://dx.doi.org/10.3389/fonc.2021.779739

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