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Afatinib and radiotherapy, with or without temozolomide, in patients with newly diagnosed glioblastoma: results of a phase I trial

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults. Amplification or overexpression of the epidermal growth factor receptor gene, part of the ErbB family, occur in approximately 40% and 60% of patients with GBM, respectively. We present data from a d...

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Detalles Bibliográficos
Autores principales:	Saran, Frank, Welsh, Liam, James, Allan, McBain, Catherine, Gattamaneni, Rao, Jefferies, Sarah, Harris, Fiona, Pemberton, Karine, Schaible, Jennifer, Bender, Shaun, Cseh, Agnieszka, Brada, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651574/ https://www.ncbi.nlm.nih.gov/pubmed/34787778 http://dx.doi.org/10.1007/s11060-021-03877-6

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