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Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy

The evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy. Twenty-three...

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Autores principales: Naar, Jan, Skalský, Ivo, Krűger, Andreas, Málek, Filip, Van Bladel, Kevin, Annest, Lon S., Moučka, Petr, Mráz, Tomáš, Reddy, Vivek Y., Neužil, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651588/
https://www.ncbi.nlm.nih.gov/pubmed/33974231
http://dx.doi.org/10.1007/s12265-021-10133-9
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author Naar, Jan
Skalský, Ivo
Krűger, Andreas
Málek, Filip
Van Bladel, Kevin
Annest, Lon S.
Moučka, Petr
Mráz, Tomáš
Reddy, Vivek Y.
Neužil, Petr
author_facet Naar, Jan
Skalský, Ivo
Krűger, Andreas
Málek, Filip
Van Bladel, Kevin
Annest, Lon S.
Moučka, Petr
Mráz, Tomáš
Reddy, Vivek Y.
Neužil, Petr
author_sort Naar, Jan
collection PubMed
description The evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy. Twenty-three subjects with transmural anterior wall scarring, LV ejection fraction 15–45%, and New York Heart Association class ≥ II were intervened using Revivent TC anchoring system. LV end-systolic volume index was reduced from 73.2 ± 27 ml at baseline to 51.5 ± 22 ml after 6 months (p < 0.001), 49.9 ± 20 ml after 2 years (p < 0.001), and 56.1 ± 16 ml after 5 years (p = 0.047). NYHA class improved significantly at 5 years compared to baseline. Six-min walk test distance increased at 2 years compared to the 6-month visit. Hybrid LV reconstruction using the anchoring system provides significant and durable LV volume reduction during 5-year follow-up in preselected patients with ischemic heart failure. GRAPHICAL ABSTRACT: [Figure: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-021-10133-9.
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spelling pubmed-86515882021-12-08 Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy Naar, Jan Skalský, Ivo Krűger, Andreas Málek, Filip Van Bladel, Kevin Annest, Lon S. Moučka, Petr Mráz, Tomáš Reddy, Vivek Y. Neužil, Petr J Cardiovasc Transl Res Original Article The evidence supporting surgical aneurysmectomy in ischemic heart failure is inconsistent. The aim of the study was to describe long-term effect of minimally invasive hybrid transcatheter and minithoracotomy left ventricular (LV) reconstruction in patients with ischemic cardiomyopathy. Twenty-three subjects with transmural anterior wall scarring, LV ejection fraction 15–45%, and New York Heart Association class ≥ II were intervened using Revivent TC anchoring system. LV end-systolic volume index was reduced from 73.2 ± 27 ml at baseline to 51.5 ± 22 ml after 6 months (p < 0.001), 49.9 ± 20 ml after 2 years (p < 0.001), and 56.1 ± 16 ml after 5 years (p = 0.047). NYHA class improved significantly at 5 years compared to baseline. Six-min walk test distance increased at 2 years compared to the 6-month visit. Hybrid LV reconstruction using the anchoring system provides significant and durable LV volume reduction during 5-year follow-up in preselected patients with ischemic heart failure. GRAPHICAL ABSTRACT: [Figure: see text] SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12265-021-10133-9. Springer US 2021-05-11 2021 /pmc/articles/PMC8651588/ /pubmed/33974231 http://dx.doi.org/10.1007/s12265-021-10133-9 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Naar, Jan
Skalský, Ivo
Krűger, Andreas
Málek, Filip
Van Bladel, Kevin
Annest, Lon S.
Moučka, Petr
Mráz, Tomáš
Reddy, Vivek Y.
Neužil, Petr
Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title_full Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title_fullStr Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title_full_unstemmed Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title_short Long-Term Results of Hybrid Left Ventricular Reconstruction in the Treatment of Ischemic Cardiomyopathy
title_sort long-term results of hybrid left ventricular reconstruction in the treatment of ischemic cardiomyopathy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651588/
https://www.ncbi.nlm.nih.gov/pubmed/33974231
http://dx.doi.org/10.1007/s12265-021-10133-9
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