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Diverse ‘just-right’ levels of chromosomal instability and their clinical implications in neoadjuvant treated gastric cancer

BACKGROUND: The Cancer Genome Atlas (TCGA) consortium described EBV positivity(+), high microsatellite instability (MSI-H), genomic stability (GS) and chromosomal instability (CIN) as molecular subtypes in gastric carcinomas (GC). We investigated the predictive and prognostic value of these subtypes...

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Detalles Bibliográficos
Autores principales: Kohlruss, Meike, Krenauer, Marie, Grosser, Bianca, Pfarr, Nicole, Jesinghaus, Moritz, Slotta-Huspenina, Julia, Novotny, Alexander, Hapfelmeier, Alexander, Schmidt, Thomas, Steiger, Katja, Gaida, Matthias M., Reiche, Magdalena, Bauer, Lukas, Ott, Katja, Weichert, Wilko, Keller, Gisela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651679/
https://www.ncbi.nlm.nih.gov/pubmed/34671125
http://dx.doi.org/10.1038/s41416-021-01587-4