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Advances in biomineralization-inspired materials for hard tissue repair

Biomineralization is the process by which organisms form mineralized tissues with hierarchical structures and excellent properties, including the bones and teeth in vertebrates. The underlying mechanisms and pathways of biomineralization provide inspiration for designing and constructing materials t...

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Autores principales: Tang, Shuxian, Dong, Zhiyun, Ke, Xiang, Luo, Jun, Li, Jianshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651686/
https://www.ncbi.nlm.nih.gov/pubmed/34876550
http://dx.doi.org/10.1038/s41368-021-00147-z
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author Tang, Shuxian
Dong, Zhiyun
Ke, Xiang
Luo, Jun
Li, Jianshu
author_facet Tang, Shuxian
Dong, Zhiyun
Ke, Xiang
Luo, Jun
Li, Jianshu
author_sort Tang, Shuxian
collection PubMed
description Biomineralization is the process by which organisms form mineralized tissues with hierarchical structures and excellent properties, including the bones and teeth in vertebrates. The underlying mechanisms and pathways of biomineralization provide inspiration for designing and constructing materials to repair hard tissues. In particular, the formation processes of minerals can be partly replicated by utilizing bioinspired artificial materials to mimic the functions of biomolecules or stabilize intermediate mineral phases involved in biomineralization. Here, we review recent advances in biomineralization-inspired materials developed for hard tissue repair. Biomineralization-inspired materials are categorized into different types based on their specific applications, which include bone repair, dentin remineralization, and enamel remineralization. Finally, the advantages and limitations of these materials are summarized, and several perspectives on future directions are discussed.
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spelling pubmed-86516862021-12-22 Advances in biomineralization-inspired materials for hard tissue repair Tang, Shuxian Dong, Zhiyun Ke, Xiang Luo, Jun Li, Jianshu Int J Oral Sci Review Article Biomineralization is the process by which organisms form mineralized tissues with hierarchical structures and excellent properties, including the bones and teeth in vertebrates. The underlying mechanisms and pathways of biomineralization provide inspiration for designing and constructing materials to repair hard tissues. In particular, the formation processes of minerals can be partly replicated by utilizing bioinspired artificial materials to mimic the functions of biomolecules or stabilize intermediate mineral phases involved in biomineralization. Here, we review recent advances in biomineralization-inspired materials developed for hard tissue repair. Biomineralization-inspired materials are categorized into different types based on their specific applications, which include bone repair, dentin remineralization, and enamel remineralization. Finally, the advantages and limitations of these materials are summarized, and several perspectives on future directions are discussed. Nature Publishing Group UK 2021-12-07 /pmc/articles/PMC8651686/ /pubmed/34876550 http://dx.doi.org/10.1038/s41368-021-00147-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Article
Tang, Shuxian
Dong, Zhiyun
Ke, Xiang
Luo, Jun
Li, Jianshu
Advances in biomineralization-inspired materials for hard tissue repair
title Advances in biomineralization-inspired materials for hard tissue repair
title_full Advances in biomineralization-inspired materials for hard tissue repair
title_fullStr Advances in biomineralization-inspired materials for hard tissue repair
title_full_unstemmed Advances in biomineralization-inspired materials for hard tissue repair
title_short Advances in biomineralization-inspired materials for hard tissue repair
title_sort advances in biomineralization-inspired materials for hard tissue repair
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651686/
https://www.ncbi.nlm.nih.gov/pubmed/34876550
http://dx.doi.org/10.1038/s41368-021-00147-z
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