Cargando…

Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

Dynamic change in subcellular localization of signaling proteins is a general concept that eukaryotic cells evolved for eliciting a coordinated response to stimuli. Mass spectrometry-based proteomics in combination with subcellular fractionation can provide comprehensive maps of spatio-temporal regu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Martinez-Val, Ana, Bekker-Jensen, Dorte B., Steigerwald, Sophia, Koenig, Claire, Østergaard, Ole, Mehta, Adi, Tran, Trung, Sikorski, Krzysztof, Torres-Vega, Estefanía, Kwasniewicz, Ewa, Brynjólfsdóttir, Sólveig Hlín, Frankel, Lisa B., Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon, Lund-Johansen, Fridtjof, Olsen, Jesper V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651693/ https://www.ncbi.nlm.nih.gov/pubmed/34876567 http://dx.doi.org/10.1038/s41467-021-27398-y

Ejemplares similares

Proteomic Analysis of Lysine Acetylation Sites in Rat Tissues Reveals Organ Specificity and Subcellular Patterns
por: Lundby, Alicia, et al.
Publicado: (2012)

A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients
por: Bekker-Jensen, Dorte B., et al.
Publicado: (2020)

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses
por: Nordgaard, Cathrine, et al.
Publicado: (2021)

Selective Autophagy of the Protein Homeostasis Machinery: Ribophagy, Proteaphagy and ER-Phagy
por: Beese, Carsten J., et al.
Publicado: (2020)

Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
por: Snieckute, Goda, et al.
Publicado: (2022)

Cell Type-Specific Subcellular Localization of Phospho-TBK1 in Response to Cytoplasmic Viral DNA
por: Suzuki, Takayuki, et al.
Publicado: (2013)

Ubiquitin and the DNA damage response: A new handle on histones
por: Bekker-Jensen, Simon, et al.
Publicado: (2012)

Activities and participation of 65-91-year-old adults: population-based study among residents of a sparsely populated and remote area in Iceland
por: Brynjolfsdottir, Margret, et al.
Publicado: (2021)

Computational and Functional Analysis of Structural Features in the ZAKα Kinase
por: Johansen, Valdemar Brimnes Ingemann, et al.
Publicado: (2023)

Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries
por: Bekker-Jensen, Dorte B., et al.
Publicado: (2020)

Benchmarking common quantification strategies for large-scale phosphoproteomics
por: Hogrebe, Alexander, et al.
Publicado: (2018)

Histone Displacement during Nucleotide Excision Repair
por: Dinant, Christoffel, et al.
Publicado: (2012)

Phospho.ELM: a database of phosphorylation sites—update 2011
por: Dinkel, Holger, et al.
Publicado: (2011)

Ribosomal stress-surveillance: three pathways is a magic number
por: Vind, Anna Constance, et al.
Publicado: (2020)

Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
por: Pedersen, Anna-Kathrine, et al.
Publicado: (2021)

High-resolution antibody array analysis of proteins from primary human keratinocytes and leukocytes
por: de la Rosa Carrillo, Daniel, et al.
Publicado: (2018)

Automated quantitative multiplex immunofluorescence in situ imaging identifies phospho-S6 and phospho-PRAS40 as predictive protein biomarkers for prostate cancer lethality
por: Shipitsin, Michail, et al.
Publicado: (2014)

Profiling of Phospho-AKT, Phospho-mTOR, Phospho-MAPK and EGFR in Non-small Cell Lung Cancer
por: Kitano, Haruhisa, et al.
Publicado: (2014)

PRMT5-mediated regulatory arginine methylation of RIPK3
por: Chauhan, Chanchal, et al.
Publicado: (2023)

ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle
por: Nordgaard, Cathrine, et al.
Publicado: (2022)

A Novel LC System Embeds Analytes in Pre-formed Gradients for Rapid, Ultra-robust Proteomics
por: Bache, Nicolai, et al.
Publicado: (2018)

Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1
por: Bekker-Jensen, Simon, et al.
Publicado: (2005)

USP7 counteracts SCF(βTrCP)- but not APC(Cdh1)-mediated proteolysis of Claspin
por: Faustrup, Helene, et al.
Publicado: (2009)

Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
por: Poulsen, Maria, et al.
Publicado: (2012)

Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids
por: Martínez-Val, Ana, et al.
Publicado: (2023)

Osmotic Stress Blocks Mobility and Dynamic Regulation of Centriolar Satellites
por: Nielsen, Julie C., et al.
Publicado: (2018)

Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage–modified chromatin
por: Melander, Fredrik, et al.
Publicado: (2008)

Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage
por: Gibbs-Seymour, Ian, et al.
Publicado: (2015)

MicroRNA Expression in Formalin-fixed Paraffin-embedded Cancer Tissue: Identifying Reference MicroRNAs and Variability
por: Boisen, Mogens Karsbøl, et al.
Publicado: (2015)

Tris(2-carbamoylguanidinium) hydrogen fluorophosphonate fluorophosphonate monohydrate
por: Fábry, Jan, et al.
Publicado: (2011)

COMPARTMENTS: unification and visualization of protein subcellular localization evidence
por: Binder, Janos X., et al.
Publicado: (2014)

A strong case for third-party testing
por: Lund-Johansen, Fridtjof
Publicado: (2023)

Ferrocenylphosphonic acid
por: Yang, Bao-Zhang, et al.
Publicado: (2011)

Ammonium benzenephosphonate
por: Lin, Zhen, et al.
Publicado: (2008)

Acetonyltriphenylphosphonium nitrate
por: Diop, Tidiane, et al.
Publicado: (2013)

Targeting proline in (phospho)proteomics
por: van der Laarse, Saar A. M., et al.
Publicado: (2020)

Phospho-Regulation of Meiotic Prophase
por: Kar, Funda M., et al.
Publicado: (2021)

Initiation of a ZAKα-dependent Ribotoxic Stress Response by the Innate Immunity Endoribonuclease RNase L
por: Xi, Jiajia, et al.
Publicado: (2023)

GSK-3 directly regulates phospho-4EBP1 in renal cell carcinoma cell-line: an intrinsic subcellular mechanism for resistance to mTORC1 inhibition
por: Ito, Hiromi, et al.
Publicado: (2016)

Lariat capping as a tool to manipulate the 5′ end of individual yeast mRNA species in vivo
por: Krogh, Nicolai, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_o10cddntpkuodhe8ihn4pj90u7