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Personalized modulation of coagulation factors using a thrombin dynamics model to treat trauma-induced coagulopathy

Current trauma-induced coagulopathy resuscitation protocols use slow laboratory measurements, rules-of-thumb, and clinician gestalt to administer large volumes of uncharacterized, non-tailored blood products. These one-size-fits-all treatment approaches have high mortality. Here, we provide signific...

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Detalles Bibliográficos
Autores principales: Ghetmiri, Damon E., Cohen, Mitchell J., Menezes, Amor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651743/
https://www.ncbi.nlm.nih.gov/pubmed/34876597
http://dx.doi.org/10.1038/s41540-021-00202-9