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eIF2B-capturing viral protein NSs suppresses the integrated stress response

Various stressors such as viral infection lead to the suppression of cap-dependent translation and the activation of the integrated stress response (ISR), since the stress-induced phosphorylated eukaryotic translation initiation factor 2 [eIF2(αP)] tightly binds to eIF2B to prevent it from exchangin...

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Detalles Bibliográficos
Autores principales:	Kashiwagi, Kazuhiro, Shichino, Yuichi, Osaki, Tatsuya, Sakamoto, Ayako, Nishimoto, Madoka, Takahashi, Mari, Mito, Mari, Weber, Friedemann, Ikeuchi, Yoshiho, Iwasaki, Shintaro, Ito, Takuhiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651795/ https://www.ncbi.nlm.nih.gov/pubmed/34876589 http://dx.doi.org/10.1038/s41467-021-27337-x

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