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A transient conformation facilitates ligand binding to the adenine riboswitch
RNAs adopt various conformations to perform different functions in cells. Incapable of acquiring intermediates, the key initiations of ligand recognition in the adenine riboswitch have not been characterized. In this work, stopped-flow fluorescence was used to track structural switches in the full-l...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652005/ https://www.ncbi.nlm.nih.gov/pubmed/34927032 http://dx.doi.org/10.1016/j.isci.2021.103512 |