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Decoding gut microbiota by imaging analysis of fecal samples

The gut microbiota plays a crucial role in maintaining health. Monitoring the complex dynamics of its microbial population is, therefore, important. Here, we present a deep convolution network that can characterize the dynamic changes in the gut microbiota using low-resolution images of fecal sample...

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Detalles Bibliográficos
Autores principales: Furusawa, Chikara, Tanabe, Kumi, Ishii, Chiharu, Kagata, Noriko, Tomita, Masaru, Fukuda, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652011/
https://www.ncbi.nlm.nih.gov/pubmed/34927025
http://dx.doi.org/10.1016/j.isci.2021.103481
Descripción
Sumario:The gut microbiota plays a crucial role in maintaining health. Monitoring the complex dynamics of its microbial population is, therefore, important. Here, we present a deep convolution network that can characterize the dynamic changes in the gut microbiota using low-resolution images of fecal samples. Further, we demonstrate that the microbial relative abundances, quantified via 16S rRNA amplicon sequencing, can be quantitatively predicted by the neural network. Our approach provides a simple and inexpensive method of gut microbiota analysis.