iNucs: inter-nucleosome interactions

MOTIVATION: Deciphering nucleosome–nucleosome interactions is an important step toward mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available. RESULTS: We developed iNucs, a user-friendly and efficient Python-based bioinformatics t...

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Detalles Bibliográficos
Autores principales: Oveisi, Mehrdad, Shukla, Manu, Seymen, Nogayhan, Ohno, Masae, Taniguchi, Yuichi, Nahata, Sunil, Loos, Remco, Mufti, Ghulam J, Allshire, Robin C, Dimitrov, Stefan, Karimi, Mohammad M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652021/
https://www.ncbi.nlm.nih.gov/pubmed/34623394
http://dx.doi.org/10.1093/bioinformatics/btab698
Descripción
Sumario:MOTIVATION: Deciphering nucleosome–nucleosome interactions is an important step toward mesoscale description of chromatin organization but computational tools to perform such analyses are not publicly available. RESULTS: We developed iNucs, a user-friendly and efficient Python-based bioinformatics tool to compute and visualize nucleosome-resolved interactions using standard pairs format input generated from pairtools. AVAILABILITYAND IMPLEMENTATION: https://github.com/Karimi-Lab/inucs/. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

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