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Extracellular Lactate Acts as a Metabolic Checkpoint and Shapes Monocyte Function Time Dependently

Elevated blood lactate levels are frequently found in critically ill patients and thought to result from tissue hypoperfusion and cellular oxygen shortage. Considering the close relationship between immune cell function and intracellular metabolism, lactate is more than a glycolytic waste molecule b...

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Detalles Bibliográficos
Autores principales:	Schenz, Judith, Heilig, Lena, Lohse, Tim, Tichy, Lucas, Bomans, Katharina, Büttner, Michael, Weigand, Markus A., Uhle, Florian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652120/ https://www.ncbi.nlm.nih.gov/pubmed/34899690 http://dx.doi.org/10.3389/fimmu.2021.729209

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