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Halofuginone Sensitizes Lung Cancer Organoids to Cisplatin via Suppressing PI3K/AKT and MAPK Signaling Pathways

Lung cancer is the leading cause of cancer death worldwide. Cisplatin is the major DNA-damaging anticancer drug that cross-links the DNA in cancer cells, but many patients inevitably develop resistance with treatment. Identification of a cisplatin sensitizer might postpone or even reverse the develo...

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Detalles Bibliográficos
Autores principales:	Li, Hefei, Zhang, Yushan, Lan, Xiaomei, Yu, Jianhua, Yang, Changshuang, Sun, Zhijian, Kang, Ping, Han, Yi, Yu, Daping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652204/ https://www.ncbi.nlm.nih.gov/pubmed/34901018 http://dx.doi.org/10.3389/fcell.2021.773048

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