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Exploration for the effect of renal function and renal replacement therapy on pharmacokinetics of remdesivir and GS‐441524 in patients with COVID‐19: A limited case series
Remdesivir, an antiviral agent for the treatment of coronavirus disease 2019 (COVID‐19), is metabolized intracellularly, with these metabolites eliminated predominantly in urine. Because of a lack of safety and pharmacokinetic (PK) data, remdesivir is not currently recommended for patients with esti...
Autores principales: | Choe, Pyoeng Gyun, Jeong, Sae Im, Kang, Chang Kyung, Yang, Liju, Lee, SeungHwan, Cho, Joo‐Youn, Han, Seung Seok, Kim, Dong Ki, Lee, Sang Min, Park, Wan Beom, Oh, Myoung‐don, Kim, Nam Joong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652615/ https://www.ncbi.nlm.nih.gov/pubmed/34761554 http://dx.doi.org/10.1111/cts.13194 |
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