In vitro data suggest that Indian delta variant B.1.617 of SARS‐CoV‐2 escapes neutralization by both receptor affinity and immune evasion

BACKGROUND: Emerged mutations can be attributed to increased transmissibility of the B.1.617 and B.1.36 Indian delta variants of SARS‐CoV‐2, most notably substitutions L452R/E484Q and N440K, respectively, which occur in the receptor‐binding domain (RBD) of the Spike (S) fusion glycoprotein. OBJECTIV...

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Detalles Bibliográficos
Autores principales: Augusto, Gilles, Mohsen, Mona O., Zinkhan, Simon, Liu, Xuelan, Vogel, Monique, Bachmann, Martin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652796/
https://www.ncbi.nlm.nih.gov/pubmed/34453338
http://dx.doi.org/10.1111/all.15065

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