Population‐based assessment of risks for severe COVID‐19 disease outcomes

Among approximately 4.6 million members of Kaiser Permanente Northern California, we examined associations of severe COVID‐19 with demographic factors and comorbidities. As of July 23, 2021, 16 182 had been hospitalized, 2416 admitted to an ICU, and 1525 died due to COVID‐19. Age was strongly associ...

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Autores principales: Zerbo, Ousseny, Lewis, Ned, Fireman, Bruce, Goddard, Kristin, Skarbinski, Jacek, Sejvar, James J., Azziz‐Baumgartner, Eduardo, Klein, Nicola P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652998/
https://www.ncbi.nlm.nih.gov/pubmed/34432371
http://dx.doi.org/10.1111/irv.12901
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author Zerbo, Ousseny
Lewis, Ned
Fireman, Bruce
Goddard, Kristin
Skarbinski, Jacek
Sejvar, James J.
Azziz‐Baumgartner, Eduardo
Klein, Nicola P.
author_facet Zerbo, Ousseny
Lewis, Ned
Fireman, Bruce
Goddard, Kristin
Skarbinski, Jacek
Sejvar, James J.
Azziz‐Baumgartner, Eduardo
Klein, Nicola P.
author_sort Zerbo, Ousseny
collection PubMed
description Among approximately 4.6 million members of Kaiser Permanente Northern California, we examined associations of severe COVID‐19 with demographic factors and comorbidities. As of July 23, 2021, 16 182 had been hospitalized, 2416 admitted to an ICU, and 1525 died due to COVID‐19. Age was strongly associated with hospitalization, ICU admission, and death. Black persons and Hispanic ethnicity had higher risk of death compared with Whites. Among the comorbidities examined, Alzheimer's disease was associated with the highest risk for hospitalization (aHR 3.19, CI: 2.88–3.52) and death (aHR 4.04, CI: 3.32–4.91). Parkinson's disease had the second highest risk of death (aHR = 2.07, CI: 1.50–2.87).
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spelling pubmed-86529982021-12-08 Population‐based assessment of risks for severe COVID‐19 disease outcomes Zerbo, Ousseny Lewis, Ned Fireman, Bruce Goddard, Kristin Skarbinski, Jacek Sejvar, James J. Azziz‐Baumgartner, Eduardo Klein, Nicola P. Influenza Other Respir Viruses Short Communications Among approximately 4.6 million members of Kaiser Permanente Northern California, we examined associations of severe COVID‐19 with demographic factors and comorbidities. As of July 23, 2021, 16 182 had been hospitalized, 2416 admitted to an ICU, and 1525 died due to COVID‐19. Age was strongly associated with hospitalization, ICU admission, and death. Black persons and Hispanic ethnicity had higher risk of death compared with Whites. Among the comorbidities examined, Alzheimer's disease was associated with the highest risk for hospitalization (aHR 3.19, CI: 2.88–3.52) and death (aHR 4.04, CI: 3.32–4.91). Parkinson's disease had the second highest risk of death (aHR = 2.07, CI: 1.50–2.87). John Wiley and Sons Inc. 2021-08-25 2022-01 /pmc/articles/PMC8652998/ /pubmed/34432371 http://dx.doi.org/10.1111/irv.12901 Text en © 2021 The Authors. Influenza and Other Respiratory Viruses published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Short Communications
Zerbo, Ousseny
Lewis, Ned
Fireman, Bruce
Goddard, Kristin
Skarbinski, Jacek
Sejvar, James J.
Azziz‐Baumgartner, Eduardo
Klein, Nicola P.
Population‐based assessment of risks for severe COVID‐19 disease outcomes
title Population‐based assessment of risks for severe COVID‐19 disease outcomes
title_full Population‐based assessment of risks for severe COVID‐19 disease outcomes
title_fullStr Population‐based assessment of risks for severe COVID‐19 disease outcomes
title_full_unstemmed Population‐based assessment of risks for severe COVID‐19 disease outcomes
title_short Population‐based assessment of risks for severe COVID‐19 disease outcomes
title_sort population‐based assessment of risks for severe covid‐19 disease outcomes
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652998/
https://www.ncbi.nlm.nih.gov/pubmed/34432371
http://dx.doi.org/10.1111/irv.12901
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