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COVID‐19 among children seeking primary paediatric care with signs of an acute infection

AIM: It can be challenging to distinguish COVID‐19 in children from other common infections. We set out to determine the rate at which children consulting a primary care paediatrician with an acute infection are infected with SARS‐CoV‐2 and to compare distinct findings. METHOD: In seven out‐patient...

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Autores principales: Hoehl, Sebastian, Schneider, Felix, Eckrich, Martin, Gründler, Tim Ole, Jerkic, Pera Silvija, Lichtenstein, Geri, Melcher, Birgit, Melcher, Hansjörg, Moebus, Ralf, Mühlfeld, Barbara, Rieger, Ilonka, Seger‐Fritz, Beate, Sgoll, Stefan, Walter, Christian, Werner, Sebastian, Herrmann, Eva, Berger, Annemarie, Ciesek, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653082/
https://www.ncbi.nlm.nih.gov/pubmed/34525232
http://dx.doi.org/10.1111/apa.16101
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author Hoehl, Sebastian
Schneider, Felix
Eckrich, Martin
Gründler, Tim Ole
Jerkic, Pera Silvija
Lichtenstein, Geri
Melcher, Birgit
Melcher, Hansjörg
Moebus, Ralf
Mühlfeld, Barbara
Rieger, Ilonka
Seger‐Fritz, Beate
Sgoll, Stefan
Walter, Christian
Werner, Sebastian
Herrmann, Eva
Berger, Annemarie
Ciesek, Sandra
author_facet Hoehl, Sebastian
Schneider, Felix
Eckrich, Martin
Gründler, Tim Ole
Jerkic, Pera Silvija
Lichtenstein, Geri
Melcher, Birgit
Melcher, Hansjörg
Moebus, Ralf
Mühlfeld, Barbara
Rieger, Ilonka
Seger‐Fritz, Beate
Sgoll, Stefan
Walter, Christian
Werner, Sebastian
Herrmann, Eva
Berger, Annemarie
Ciesek, Sandra
author_sort Hoehl, Sebastian
collection PubMed
description AIM: It can be challenging to distinguish COVID‐19 in children from other common infections. We set out to determine the rate at which children consulting a primary care paediatrician with an acute infection are infected with SARS‐CoV‐2 and to compare distinct findings. METHOD: In seven out‐patient clinics, children aged 0–13 years with any new respiratory or gastrointestinal symptoms and presumed infection were invited to be tested for SARS‐CoV‐2. Factors that were correlated with testing positive were determined. Samples were collected from 25 January 2021 to 01 April 2021. RESULTS: Seven hundred and eighty‐three children participated in the study (median age 3 years and 0 months, range 1 month to 12 years and 11 months). Three hundred and fifty‐eight were female (45.7%). SARS‐CoV‐2 RNA was detected in 19 (2.4%). The most common symptoms in children with as well as without detectable SARS‐CoV‐2 RNA were rhinitis, fever and cough. Known recent exposure to a case of COVID‐19 was significantly correlated with testing positive, but symptoms or clinical findings were not. CONCLUSION: COVID‐19 among the children with symptoms of an acute infection was uncommon, and the clinical presentation did not differ significantly between children with and without evidence of an infection with SARS‐CoV‐2.
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spelling pubmed-86530822021-12-08 COVID‐19 among children seeking primary paediatric care with signs of an acute infection Hoehl, Sebastian Schneider, Felix Eckrich, Martin Gründler, Tim Ole Jerkic, Pera Silvija Lichtenstein, Geri Melcher, Birgit Melcher, Hansjörg Moebus, Ralf Mühlfeld, Barbara Rieger, Ilonka Seger‐Fritz, Beate Sgoll, Stefan Walter, Christian Werner, Sebastian Herrmann, Eva Berger, Annemarie Ciesek, Sandra Acta Paediatr Regular Articles & Brief Reports AIM: It can be challenging to distinguish COVID‐19 in children from other common infections. We set out to determine the rate at which children consulting a primary care paediatrician with an acute infection are infected with SARS‐CoV‐2 and to compare distinct findings. METHOD: In seven out‐patient clinics, children aged 0–13 years with any new respiratory or gastrointestinal symptoms and presumed infection were invited to be tested for SARS‐CoV‐2. Factors that were correlated with testing positive were determined. Samples were collected from 25 January 2021 to 01 April 2021. RESULTS: Seven hundred and eighty‐three children participated in the study (median age 3 years and 0 months, range 1 month to 12 years and 11 months). Three hundred and fifty‐eight were female (45.7%). SARS‐CoV‐2 RNA was detected in 19 (2.4%). The most common symptoms in children with as well as without detectable SARS‐CoV‐2 RNA were rhinitis, fever and cough. Known recent exposure to a case of COVID‐19 was significantly correlated with testing positive, but symptoms or clinical findings were not. CONCLUSION: COVID‐19 among the children with symptoms of an acute infection was uncommon, and the clinical presentation did not differ significantly between children with and without evidence of an infection with SARS‐CoV‐2. John Wiley and Sons Inc. 2021-09-20 2021-12 /pmc/articles/PMC8653082/ /pubmed/34525232 http://dx.doi.org/10.1111/apa.16101 Text en © 2021 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Regular Articles & Brief Reports
Hoehl, Sebastian
Schneider, Felix
Eckrich, Martin
Gründler, Tim Ole
Jerkic, Pera Silvija
Lichtenstein, Geri
Melcher, Birgit
Melcher, Hansjörg
Moebus, Ralf
Mühlfeld, Barbara
Rieger, Ilonka
Seger‐Fritz, Beate
Sgoll, Stefan
Walter, Christian
Werner, Sebastian
Herrmann, Eva
Berger, Annemarie
Ciesek, Sandra
COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title_full COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title_fullStr COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title_full_unstemmed COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title_short COVID‐19 among children seeking primary paediatric care with signs of an acute infection
title_sort covid‐19 among children seeking primary paediatric care with signs of an acute infection
topic Regular Articles & Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653082/
https://www.ncbi.nlm.nih.gov/pubmed/34525232
http://dx.doi.org/10.1111/apa.16101
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